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Open Source AI Agent Platforms using Python

A curated collection of the best open source platforms for creating and managing autonomous AI agents. using Python.

Structured control layer for customer-facing AI agents
  • Stars


    18,253
  • Last commit


    1 month ago
  • License


    Apache-2.0
A conversational AI server that manages agent behavior through context-aware guidelines, keeping responses consistent, auditable, and aligned at scale.

Open Source Alternative to:

Desktop AI agent with persistent memory across platforms
  • Stars


    232,972
  • Last commit


    6 hours ago
  • License


    MIT
Cross-platform desktop agent from Nous Research that connects to Telegram, Discord, Slack, WhatsApp, and more, with persistent memory, scheduling, and isolated sandboxing.

Open Source Alternative to:

Build and deploy AI agents and RAG pipelines visually
  • Stars


    152,911
  • Last commit


    6 hours ago
  • License


    Unknown
Visual platform for building agentic workflows, RAG pipelines, and LLM-powered apps. Supports hundreds of models, MCP integration, and self-hosted deployment.

Open Source Alternative to:

Visual builder for AI agents and RAG pipelines
  • Stars


    153,474
  • Last commit


    6 hours ago
  • License


    MIT
Build, deploy, and iterate on AI agents, RAG applications, and MCP servers using a drag-and-drop visual interface backed by Python.

Open Source Alternative to:

One interface for all your AI models and conversations
  • Stars


    42,234
  • Last commit


    6 hours ago
  • License


    MIT
Chat with multiple AI providers through a single self-hostable interface, with support for custom agents, file uploads, plugins, and multi-user access control.

Open Source Alternative to:

Model-agnostic platform for building intelligent AI agents
  • Stars


    41,785
  • Last commit


    6 hours ago
  • License


    Apache-2.0
Open-source platform that enables developers to create, deploy and monitor AI agents with built-in memory, knowledge integration, and external tool connectivity.

Open Source Alternative to:

Build AI copilots for your product in hours, not months
  • Stars


    36,849
  • Last commit


    6 hours ago
  • License


    MIT
Integrate production-ready AI copilots into any product quickly and easily with CopilotKit's open-source platform.

Open Source Alternative to:

Build and deploy AI agents with advanced memory
  • Stars


    24,304
  • Last commit


    4 days ago
  • License


    Apache-2.0
Letta is an open-source platform for creating AI agents with built-in memory, reasoning, and support for thousands of tools.

Open Source Alternative to:

AI agent that autonomously handles real-world tasks
  • Stars


    20,119
  • Last commit


    6 hours ago
  • License


    Apache-2.0
Open source AI assistant that executes complex tasks from market research to travel planning through natural conversation, with full transparency and community-driven development.

Open Source Alternative to:

Build stateful backends with in-memory actors
  • Stars


    6,069
  • Last commit


    6 hours ago
  • License


    Apache-2.0
Open-source infrastructure for long-lived, in-memory processes called Actors. Combines state and compute with sub-millisecond latency, realtime capabilities, and horizontal scaling.

Open Source Alternative to:

Build reliable AI agents with unified tool integration
  • Stars


    4,880
  • Last commit


    3 months ago
  • License


    Apache-2.0
Platform for connecting AI agents to 500+ tools with built-in multi-tenant auth management and granular permissions using either function calling or a unified MCP server

Open Source Alternative to:

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