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Open Source AI Personal Assistants using Python

A curated collection of the best open source aI-powered assistants for personal productivity and task automation. using Python.

Keyboard-first email client with AI, chat, and tasks
  • Stars


    4,731
  • Last commit


    8 hours ago
  • License


    AGPL-3.0
An AI-powered email client that combines inbox management, chat, tasks, and AI agents in one shared workspace, built for keyboard-driven workflows.

Open Source Alternative to:

Private AI chat with zero-access encryption
  • Stars


    5,642
  • Last commit


    1 day ago
  • License


    GPL-3.0
AI chat assistant from Proton that stores conversations with zero-access encryption, never logs chats, and never uses your data to train models.

Open Source Alternative to:

An AI assistant that acts, not just answers
  • Stars


    392,431
  • Last commit


    5 hours ago
  • License


    MIT
A personal AI assistant that connects to your existing chat apps and handles real tasks like email, calendar, and flight check-ins on your behalf.

Open Source Alternative to:

Desktop AI agent with persistent memory across platforms
  • Stars


    255,041
  • Last commit


    5 hours ago
  • License


    MIT
Cross-platform desktop agent from Nous Research that connects to Telegram, Discord, Slack, WhatsApp, and more, with persistent memory, scheduling, and isolated sandboxing.

Open Source Alternative to:

Self-hosted AI agent for chat, automation, and workflows
  • Stars


    49,166
  • Last commit


    5 hours ago
  • License


    MIT
Lightweight, self-hosted AI agent that runs in a web UI, terminal, or chat app, handling long-running workflows with controlled token budgets.

Open Source Alternative to:

Personal AI agent for messaging apps, containerized
  • Stars


    30,966
  • Last commit


    5 hours ago
  • License


    MIT
Self-hosted AI agent that connects to WhatsApp, Telegram, Slack, and a dozen more messaging apps, running each agent in an isolated Docker container with credential injection via a secure vault.

Open Source Alternative to:

Favicon of Jan

Jan

AI
Run AI models locally or connect to cloud, privately
  • Stars


    45,010
  • Last commit


    5 hours ago
  • License


    Apache-2.0
Jan runs open-source AI models on your own hardware or connects to cloud providers like OpenAI, Anthropic, and Google, keeping your conversations off third-party servers.

Open Source Alternative to:

Self-hosted AI agent with 70+ providers and 30+ channels
  • Stars


    32,996
  • Last commit


    7 hours ago
  • License


    Apache-2.0
A single Rust binary that runs a personal AI agent on your own hardware, connecting to 70+ LLM providers and 30+ messaging channels with built-in sandboxing and cryptographic tool receipts.

Open Source Alternative to:

AI second brain for research, automation, and personal agents
  • Stars


    37,742
  • Last commit


    3 months ago
  • License


    AGPL-3.0
Self-hostable AI assistant that connects to your docs and the web, lets you build agents, schedule automations, and run research with verifiable citations.

Open Source Alternative to:

Desktop multi-agent workforce for automating real tasks
  • Stars


    15,599
  • Last commit


    2 days ago
  • License


    Apache-2.0
Self-hostable desktop app that runs a coordinated team of AI agents to browse the web, manage files, execute terminal commands, and complete complex workflows.

Open Source Alternative to:

AI agent runtime with encrypted enclaves for your secrets
  • Stars


    12,662
  • Last commit


    16 hours ago
  • License


    Apache-2.0
Runs AI agents inside Trusted Execution Environments on NEAR AI Cloud, keeping credentials encrypted and invisible to the model at all times.

Open Source Alternative to:

Your open-source personal assistant for server automation
  • Stars


    17,588
  • Last commit


    7 days ago
  • License


    MIT
Leon is an AI-powered virtual assistant that lives on your server, automating tasks and managing your digital life with privacy and customization.

Open Source Alternative to:

Self-hosted enterprise agent platform with real permissions
  • Stars


    6,654
  • Last commit


    10 hours ago
  • License


    MIT
Deploy AI agents inside your own infrastructure with document-grounded answers, computer use, and support for any AG-UI-compatible agent framework.

Open Source Alternative to:

A team of AI agents in a chat app, on your own machine
  • Stars


    5,149
  • Last commit


    5 hours ago
  • License


    Apache-2.0
Run a team of AI agents locally on your own API keys and subscriptions, with scheduled tasks, computer use, and Gmail, GitHub and Slack integrations.

Open Source Alternative to:

AI-powered automation that lives in your Slack workspace
  • Stars


    1,098
  • Last commit


    6 months ago
  • License


    Apache-2.0
Connect all your apps through Pearl, an AI assistant that automates workflows directly in Slack. No coding required - save 10+ hours weekly with intelligent task automation.

Open Source Alternative to:

Dictate faster and control your Mac with voice
  • Stars


    656
  • Last commit


    26 days ago
  • License


    MIT
Free, open-source macOS voice assistant that transcribes speech, applies AI transformations, and controls apps hands-free. No subscription, no training required.

Open Source Alternative to:

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